Vectors are delivery vehicles or carriers that are used to encapsulate therapeutic genes for delivery to cells or tissues. Scientists use several different types of vector, such as viral and non-viral vectors. The type of vector is decided based on factors including transgene size, target cell type, and research environment. For example, for in vitro or ex vivo delivery of a large transgene, the researcher might select a lentiviral or a transposon vector, whereas, for in vivo delivery of a small transgene in muscle tissue, an AAV vector might be an optimal choice.
This entry was provided by the doctoral students of the GetRADI collaborative network. GetRADI is funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.