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Designer nuclease

Designer nucleases are engineered enzymes designed to target and modify specific DNA sequences in the genome with high precision. They are used in genome editing technologies such as CRISPR-Cas9, zinc finger nucleases (ZFNs), and transcription activator-like effector nucleases (TALENs). These nucleases can induce DNA breaks at desired locations, allowing for precise modifications such as gene knockout, gene insertion, or gene correction.

 

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This entry was provided by the doctoral students of the GetRADI collaborative network. GetRADI is funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or the European Research Executive Agency. Neither the European Union nor the granting authority can be held responsible for them.

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